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Updated: Aug 29, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
[Vaccination and the respiratory tract--what should we know?]
Calil Kairalla Farhat1, Otávio Augusto Leite Cintra, Miguel W Tregnaghi
1Pediatria, Universidade Federal de São Paulo, São Paulo, SP. dipe@nvcnet.com.br
Objective:
This article aims at presenting a review of the main vaccines used in the pediatric population with direct impact on the prevention of infectious processes of the respiratory tract in children.
Sources:
Data from articles published in national and international scientific journals. The data were selected by means of direct search or search in the Lilacs and Medline databases.
Summary Of The Findings:
This article was structured in topics, presenting issues related to immunization against frequent pathogens of the respiratory tract in human beings: Haemophilus influenza, influenza virus, respiratory syncytial virus and Streptococcus pneumoniae.
Conclusions:
The prevention of respiratory diseases through immunization is one of the main measures for the control of respiratory infection. These new vaccines, especially against Haemophilus influenza, have been available for some years with acknowledged efficacy. Now, the vaccine against Streptococcus pneumoniae (heptavalent vaccine) leads to a new perspective towards the management of respiratory diseases in children. In risk populations, the control of viral diseases through immunization, actively against the influenza virus and passively against the syncytial respiratory virus, is also an efficient measure to reduce respiratory disease.
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