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Updated: Aug 29, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
[Surgical treatment of epilepsies in children]
1Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.
Insights
Pediatric epilepsy surgery offers gratifying results, with 60-100% achieving seizure freedom. Beyond seizure control, surgery can improve behavior, schooling, and social outcomes for children.
Area of Science:
- Pediatric Neurology
- Neurosurgery
- Epileptology
Background:
- Epilepsy in children and adolescents often stems from developmental abnormalities and low-grade tumors.
- Extratemporal resections and hemispherectomies are prevalent surgical approaches in pediatric epilepsy cases.
- Hippocampal sclerosis is a less common finding in pediatric epilepsy surgery series.
Purpose of the Study:
- To conduct a literature review on the surgical treatment of epilepsy in children.
- To analyze the efficacy and outcomes of epilepsy surgery in pediatric populations.
Main Methods:
- Critical analysis of existing literature on pediatric epilepsy surgery.
- Review of studies focusing on surgical interventions for childhood epilepsy.
Main Results:
- Seizure-free outcomes are less frequent with extratemporal/multilobar resections compared to temporal resections in children, though results remain gratifying.
- Pediatric epilepsy surgery series report 60-100% good seizure outcomes.
- Significant improvements are observed in behavior (30-40%), school attendance (16%), and social life (2/3) post-surgery.
Conclusions:
- Epilepsy surgery is a viable therapeutic option for carefully selected children.
- Comprehensive assessment of quality of life, including developmental, social, and behavioral aspects, is crucial.
- The field of pediatric epilepsy surgery is expected to expand, emphasizing improved patient quality of life.
Abstract:
OBJECTIVE: To review the literature on surgical treatment of epilepsy in children. SOURCES: This review article is based on critical analysis of literature concerning epilepsy surgery for children. SUMMARY OF THE FINDINGS: In children and adolescents, developmental abnormalities and low-grade tumors predominate as causes and types of epilepsies. Extratemporal resections and hemispherectomies are common in pediatric series, and hippocampal sclerosis is rare. Seizure-free outcome is significantly less frequent after extratemporal or multilobar resection than after temporal resection in children than in adults, but the results are gratifying in both groups. Also, a global outcome, including parental satisfaction, developmental and social outcome, as well as activities of daily living (ADL), schooling, and behavioral changes should be considered. Pediatric epilepsy surgical series show that 60-100% of the patients have a good seizure outcome. Roughly 30 to 40% of patients improve some aspects of their behavior such as attention, aggressiveness, and hyperactivity and 16% of those start to attend school after surgery. Parents noted improvement of their social life in about 2/3 of children. CONCLUSIONS:Surgery for epilepsy has now become a realistic therapeutic option for selected children and the field is likely to increase in the near future. Surgical therapy should not be considered unless there is a reasonably good chance of improving the patientacute;s quality of life.
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