Two potential mechanisms of oxaliplatin-induced haemolytic anaemia in a single patient

Ralf-Dieter Hofheinz1, Xuan-Duc Nguyen, Dieter Buchheidt

  • 1III. Medical Clinic, University Hospital Mannheim, University of Heidelberg, Wiesbadener Strasse 7-11, 68167 Mannheim, Germany. ralf.hofheinz@med3.ma.uni-heidelberg.de

Only two patients with adequately documented oxaliplatin-induced autoimmune haemolytic anaemia have previously been reported. We report here a third patient with an immune-haematological finding favouring a bispecific mechanism (immune-complex and penicillin type) of oxaliplatin-induced haemolysis.