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Updated: Aug 29, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Modulation of sensorimotor performances and cognition abilities induced by RPMS: clinical and experimental
Albrecht Struppler1, Bernhard Angerer, Peter Havel
1Sensorimotor Integration Research Group, Klinikum Rechts der Isar der TUM, Psychiatrische Klinik, Ismaningerstr. 22, 81675 Munich, Germany. struppler@lrz.tum.de
Abstract:
The investigations presented in this chapter lead to the conclusion that proprioceptive afferent inflow to the CNS induced by RPMS elicits various modulatory effects in sensorimotor and cognitive systems. Since the build-up of the conditioning effects is delayed and the effects itself are long-lasting, it has to be assumed that these effects are caused via neuromodulators. Therefore, the presented approach is promising to improve sensorimotor and cognitive disturbances after lesions in the CNS, e.g. after a stroke, by facilitation of reorganization.

