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Related Experiment Videos

Priming Reduced Extracorporeal Circulation Setup (PRECiSe) with the DeltaStream diagonal pump.

Sven Beholz1, Michael Kessler, Ralf Thölke

  • 1Department of Cardiovascular Surgery, Charité, Humboldt-University Berlin, Berlin, Germany. sven.beholz@charite.de

Artificial Organs
|December 18, 2003
PubMed
Summary

A new low priming system for cardiopulmonary bypass (CPB) called PRECiSe significantly reduces priming volume. This innovation minimizes hemodilution and transfusion needs during coronary artery bypass grafting (CABG) procedures.

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Area of Science:

  • Cardiovascular Surgery
  • Medical Device Technology

Background:

  • Traditional cardiopulmonary bypass (CPB) systems often require large priming volumes, leading to hemodilution.
  • Existing low priming systems are typically limited in functionality, especially for beating heart procedures.
  • Minimizing priming volume is crucial for reducing complications associated with extracorporeal circulation.

Purpose of the Study:

  • To introduce and evaluate the PRECiSe (Priming Reduced Extracorporeal Circulation Setup) system.
  • To assess the feasibility and safety of PRECiSe for coronary artery bypass grafting (CABG).
  • To determine the impact of PRECiSe on priming volume and hemodilution.

Main Methods:

  • Description of the PRECiSe system, including the DeltaStream diagonal pump, membrane oxygenator, filter, and reservoir.

Related Experiment Videos

  • Utilized autologous blood for priming to further reduce hemodilution.
  • Conducted a safety study involving 11 patients undergoing CABG using the PRECiSe system.

    • Main Results:

    • The PRECiSe system successfully provided all features of cardiopulmonary bypass.
    • Mean priming volume was reduced to 268.5 ml.
    • The system was used in 11 CABG patients without adverse effects, demonstrating minimal hemodilution and transfusion requirements.

    Conclusions:

    • PRECiSe is a novel low priming system for extracorporeal circulation that effectively supports CPB.
    • The system significantly reduces priming volume, leading to minimal hemodilution and reduced transfusion needs in CABG patients.
    • PRECiSe offers a safe and effective alternative for CPB, particularly in reducing complications associated with fluid shifts.