Related Experiment Video
Updated: Aug 15, 2026
08:40
Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
Does residual urine predispose to urinary tract infection?
S J Hampson1, J G Noble, D Rickards
1Department of Urology, Middlesex Hospital, London.
British Journal of Urology
|November 1, 1992
Summary
This study found no significant link between high post-micturition residual urine volumes and urinary tract infections. Bladder emptying volumes greater than 100 ml did not show a higher rate of bacterial infection or pyuria.
Area of Science:
- Urology
- Infectious Diseases
- Medical Research
Background:
- The association between post-micturition residual urine and urinary tract infections (UTIs) requires further clarification.
- Understanding bladder emptying dynamics is crucial for managing urinary health.
Purpose of the Study:
- To investigate the correlation between residual urinary volume after voiding and the incidence of UTIs.
- To compare infection and pyuria rates in patients with residual urine volumes above and below 100 ml.
Main Methods:
- Retrospective analysis of 342 studies focusing on bladder emptying.
- Comparison of bacterial infection and pyuria rates based on residual urine volume thresholds (>100 ml vs. <100 ml).
Main Results:
- Analysis of 219 studies with residual volume >100 ml showed 49 with pyuria.
- Analysis of 198 studies with residual volume <100 ml showed 28 with infection.
- In cases with residual volumes >100 ml, 33/123 had pyuria and 19/109 had infection.
- No significant increase in infection rates was observed in patients with large residual urinary volumes.
Conclusions:
- The study suggests no definitive correlation between post-micturition residual urine volume and the occurrence of urinary tract infections.
- Elevated residual urine volumes do not appear to be a significant risk factor for UTIs based on this analysis.
Related Concept Videos
01:26Urinary Tract Infection I: Introduction
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
01:25Urinary Tract Infection II: Pathophysiology
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
01:27Acute Pyelonephritis I: Introduction
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
01:26Urine Studies II: Urine Culture and Sensitivity Test
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
01:28Microbiota of the Urogenital Tract
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...