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Updated: Jul 19, 2026

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The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation
Published on: August 21, 2012
Samuel Pepys and his bladder stone
1Department of Urology, Wellington Hospital, New Zealand.
British Journal of Urology
|November 1, 1992
Summary
Samuel Pepys underwent a successful bladder stone surgery at age 25, despite the risks of the era. This historical medical case highlights early surgical outcomes and patient survival.
Area of Science:
- Medical History
- Surgical Innovation
Background:
- Samuel Pepys faced severe agony from a bladder stone in his youth.
- He chose surgical intervention at 25, understanding the era's limited medical knowledge and high risks.
Discussion:
- The surgery was performed perineally without anesthesia by a barber surgeon.
- Despite the era's ignorance of sepsis, the operation was successful, and Pepys survived.
Key Insights:
- The case demonstrates a successful, albeit risky, surgical outcome in the 17th century.
- Pepys's survival led to a prominent career and lasting fame, notably through his diary.
Outlook:
- This historical account offers insights into the evolution of surgical safety and patient care.
- It underscores the importance of historical medical records in understanding past practices and outcomes.
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