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Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
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Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

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Alternative splicing of the human MUC2 gene

Lawrence R Sternberg1, James C Byrd, Gunnar C Hansson

  • 1Gastrointestinal Cancer Research Laboratory, Henry Ford Health Sciences Center, 2799 West Grand Blvd, Detroit, MI 48202, USA.

Archives of Biochemistry and Biophysics
|December 18, 2003
PubMed

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Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
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