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Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide
Marco Palma1, Darrow DeLuca, Stefan Worgall
1Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York 10021, USA.
Abstract:
Pseudomonas aeruginosa must often overcome a high concentration of oxidants to successfully infect the human host. We report here the results of a transcriptome profiling comparing cells treated with H(2)O(2) and untreated controls. The data indicate that the early response of P. aeruginosa to H(2)O(2) consists of an upregulation of protective mechanisms and a downregulation of primary metabolism.
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