Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A personal computer program for large-scale comparisons of related nucleotide sequences.

R Schipper1, M Kenter, T Rinke de Wit

  • 1Department of Immunohaematology and Blood Bank, Leiden University Hospital, The Netherlands.

Computer Applications in the Biosciences : CABIOS
|December 1, 1992
PubMed
Summary

A new computer program, COMPSEQ, aids in analyzing nucleotide and amino acid sequences. It highlights differences in aligned sequences, simplifying comparative analysis for researchers.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consequences of intra-canopy and top LED lighting for uniformity of light distribution in a tomato crop.

Frontiers in plant science·2023
Same author

The present and future disease burden of hepatitis C virus infections with today's treatment paradigm: Volume 4.

Journal of viral hepatitis·2017
Same author

Historical epidemiology of hepatitis C virus in select countries-volume 4.

Journal of viral hepatitis·2017
Same author

Strategies to manage hepatitis C virus infection disease burden-Volume 4.

Journal of viral hepatitis·2017
Same author

[GIP-like findings with a special spectrum of causes].

Der Pathologe·2014
Same author

The role of magnetic resonance imaging in assessing residual disease and pathologic complete response in breast cancer patients receiving neoadjuvant chemotherapy: a systematic review.

Insights into imaging·2013

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Molecular Biology

Background:

  • Comparative analysis of nucleotide and amino acid sequences is crucial in molecular biology.
  • Identifying differences between related sequences can be challenging with large datasets.

Purpose of the Study:

  • To introduce COMPSEQ, a novel personal computer program for sequence analysis.
  • To facilitate the comparison of pre-aligned exonic nucleotide and amino acid sequences.

Main Methods:

  • Development of the COMPSEQ program for sequence data processing.
  • Implementation of algorithms to align and translate nucleotide sequences.
  • Feature to suppress sequence concordances and emphasize differences.

Main Results:

Related Experiment Videos

  • COMPSEQ provides informative listings of aligned nucleotide and translated amino acid sequences.
  • The program effectively highlights variations between related sequences by focusing on differences.
  • Enables triplet-oriented analyses within specified reading frames.

Conclusions:

  • COMPSEQ offers an efficient tool for comparative sequence analysis.
  • The program simplifies the identification of sequence variations.
  • A valuable resource for researchers in bioinformatics and molecular biology.