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Published on: October 24, 2018
Psychological stress and cortisol secretion in anhedonic alcoholic men
1Département de Pharmacologie, Hôpital Pitié-Salpêtrière, 47, Bd de l'Hôpital, 75634 Paris 13, France.
Abstract:
We investigated plasma cortisol in a psychological stress paradigm in seven weaned anhedonic alcoholics in comparison with seven age-matched healthy controls. Alcoholics had significantly higher mean plasma cortisol at baseline and no increase following a psychological stress paradigm. Anhedonic alcoholics judged the experimental situation less agreeable than controls. Anhedonic alcoholics may have blunted cortisol response to psychological stress.
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