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Updated: Aug 29, 2026

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The Indirect Neuron-astrocyte Coculture Assay: An In Vitro Set-up for the Detailed Investigation of Neuron-glia Interactions
Published on: November 14, 2016
Neurons and brain macrophages regulate connexin expression in cultured astrocytes
Annette Koulakoff1, William Même, Charles-Felix Calvo
1INSERM U114, Collège de France, Paris, France.
Cell Communication & Adhesion
|December 19, 2003
Abstract:
Neurons and brain macrophages (BM), respectively, increase and inhibit gap junctional communication (GJC) and connexin expression in cultured astrocytes. Thus, in brain diseases and injuries, neuronal death associated with the BM activation may decrease GJC in astrocytes and therefore have a physiopathological relevance.

