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The EMBL Nucleotide Sequence Database.

Tamara Kulikova1, Philippe Aldebert, Nicola Althorpe

  • 1EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. kulikova@ebi.ac.uk

Nucleic Acids Research
|December 19, 2003
PubMed
Summary

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This summary is machine-generated.

The EMBL Nucleotide Sequence Database provides access to public nucleotide sequences through international collaboration. It offers various tools for data submission and sequence similarity searching, ensuring up-to-date information.

Area of Science:

  • Bioinformatics
  • Molecular Biology
  • Genomics

Background:

  • The European Molecular Biology Laboratory (EMBL) Nucleotide Sequence Database is a key resource for public genetic information.
  • It is part of a global effort, collaborating with DDBJ and GenBank for data synchronization.

Purpose of the Study:

  • To describe the EMBL Nucleotide Sequence Database's resources and accessibility.
  • To highlight data submission methods and sequence analysis tools.

Main Methods:

  • Data integration from public sources and international partners (DDBJ, GenBank).
  • Web-based submission tools (Webin) and automated procedures for large-scale data.
  • Sequence similarity searching using tools like BLAST and FASTA.

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Main Results:

  • Quarterly database releases ensure access to the latest nucleotide sequence data.
  • The Sequence Retrieval System (SRS) integrates multiple molecular biology databases.
  • Tools are available for comparing user sequences against the comprehensive database.

Conclusions:

  • The EMBL Nucleotide Sequence Database is a vital, synchronized resource for molecular biology research.
  • Easy access and diverse analysis tools facilitate genetic data utilization.