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Related Experiment Videos

The mouse Gene Expression Database (GXD): updates and enhancements.

David P Hill1, Dale A Begley, Jacqueline H Finger

  • 1The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.

Nucleic Acids Research
|December 19, 2003
PubMed
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The Gene Expression Database (GXD) offers integrated mouse gene expression data, aiding research into development and disease. Enhanced features improve access to gene expression profiles for researchers.

Area of Science:

  • * Genomics and Bioinformatics
  • * Developmental Biology
  • * Mouse Genetics

Background:

  • * The Gene Expression Database (GXD) is a vital community resource for accessing gene expression information in laboratory mice.
  • * It integrates diverse expression data types across various mouse strains and mutants.
  • * GXD aligns with the Gene Ontology (GO) project, classifying genes by function, process, and cellular component.

Purpose of the Study:

  • * To provide a comprehensive resource for mouse gene expression data.
  • * To integrate gene expression information with genetic, genomic, and phenotypic data.
  • * To facilitate insights into the molecular biology of development and disease.

Main Methods:

  • * Collection and integration of diverse gene expression data.

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  • * Classification of genes and gene products using the Gene Ontology (GO).
  • * Integration with Mouse Genome Informatics (MGI) databases.

    • Main Results:

    • * GXD provides detailed expression profiles for mouse genes.
    • * Integration with MGI databases contextualizes expression data within genetic and phenotypic information.
    • * Daily data additions and improved query/display features enhance usability.

    Conclusions:

    • * GXD serves as a crucial resource for understanding mouse gene expression.
    • * Data integration provides valuable insights into molecular biology, development, and disease.
    • * Ongoing improvements enhance user accessibility and data visualization for research needs.