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Related Experiment Videos

24-h hydration status: parameters, epidemiology and recommendations.

F Manz1, A Wentz

  • 1Research Institute of Child Nutrition, Dortmund, Germany. manz@fke-do.de

European Journal of Clinical Nutrition
|December 19, 2003
PubMed
Summary

Urine osmolality (Uosm) varies significantly across age groups, individuals, and cultures. A new

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Area of Science:

  • Physiology
  • Human Hydration
  • Nutritional Science

Background:

  • Urine osmolality (Uosm) is a key indicator of hydration status.
  • Significant ontogenetic, individual, and cultural variations in Uosm exist.
  • Uosm differs markedly between fetuses/infants and children/adults.

Purpose of the Study:

  • To review factors influencing Uosm in different populations.
  • To introduce the concept of 'free-water reserve' for quantifying 24-hour euhydration.
  • To analyze hydration status in children using Uosm and free-water reserve.

Main Methods:

  • Review of existing data on Uosm in infants, children, and adults.
  • Analysis of urine volume and Uosm in 189 boys (DONALD Study).
  • Calculation of free-water reserve based on Uosm and water intake.

Main Results:

  • Intercultural differences in mean 24-h Uosm are substantial (e.g., Germany, USA, Poland).
  • Gender differences in Uosm are common in industrialized countries.
  • In studied boys, median free-water reserve was 11 ml/24-h, indicating adequate hydration.

Conclusions:

  • Uosm and free-water reserve are valuable metrics for assessing hydration.
  • Understanding variations in Uosm is crucial for public health and epidemiology.
  • Further global data on Uosm and free-water reserve can inform health studies.

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