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Updated: Aug 15, 2026

Intravascular Delivery of Biologics to the Rat Kidney
Published on: September 1, 2016
[Preliminary results of intravenous immunoglobulins in treating patients with vasculitis]
A Antonelli1, G Agostini, S Agostini
1Clinica Medica II, Università degli Studi di Pisa.
Four patients affected with vasculitis syndrome (1 systemic vasculitis, 3 cutaneous vasculitis) were treated with "intravenous immunoglobulin" (IVIG). Two patients (1 systemic vasculitis, 1 cutaneous vasculitis) presented an improvement of clinical syndrome, while the other 2 patients presented a stable remission; in all patients biochemical amelioration or normalization was observed too. These data confirm that IVIG may be useful in treatment of systemic vasculitis and, for the first time to our knowledge, suggest that IVIG may be an effective treatment in cutaneous vasculitis.
Four patients affected with vasculitis syndrome (1 systemic vasculitis, 3 cutaneous vasculitis) were treated with "intravenous immunoglobulin" (IVIG). Two patients (1 systemic vasculitis, 1 cutaneous vasculitis) presented an improvement of clinical syndrome, while the other 2 patients presented a stable remission; in all patients biochemical amelioration or normalization was observed too. These data confirm that IVIG may be useful in treatment of systemic vasculitis and, for the first time to our knowledge, suggest that IVIG may be an effective treatment in cutaneous vasculitis.
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