[The influence of hyperthyroidism on selected parameters of oxidant-antioxidant balance on animal model]

The aim of the experiment was to examine the influence of increased concentration of thyroid hormones on selected parameters of oxidant-antioxidant balance through the analysis of the antioxidant enzymes activity, the content of antioxidant vitamins, and the concentration of the unsaturated fatty acids peroxidation (TBARS). Administration of levothyroxine of the dose 100 micrograms/kg of body mass to rabbits for 21 days caused the increase of TBARS concentration, the decrease of concentration of vitamins C and E, and the increase of SOD activity.