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Postcolumn HPLC detection of mono- and oligosaccharides with a chemosensor
Kyu Kwang Kim1, Jorge O Escobedo, Nadia N St Luce
1Department of Chemistry, Louisiana State University, Baton Rouge, LA 70803, USA.
Organic Letters
|December 20, 2003
Abstract:
Novel chromophoric compound 1 promotes the HPLC postcolumn detection of mono- and oligosaccharides. The detection of chromatographic peaks in the visible region for glucose, fructose, maltodextrins, sialic acid, and a ganglioside can be accomplished with a standard UV-vis detector. The use of selective, reversible binding agents in automated HPLC assays should allow for improved monitoring of specific analytes as well as material recovery. [structure: see text]