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Updated: Jul 23, 2026

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
Published on: October 13, 2011
Particle transport in asymmetric scanning-line optical tweezers
B Liesfeld1, R Nambiar, J C Meiners
1Department of Physics and Biophysics Research Division, University of Michigan, Ann Arbor, Michigan 48109-1120, USA. ben.liesfeld@umich.edu
Abstract:
We describe a scanning-line optical tweezing technique with an asymmetric beam profile in the back focal plane of the microscope objective. The motion of a trapped particle along the scan line is studied as a function of beam asymmetry, and it is shown that this technique can be used to exert a constant lateral force on the particle, realizing purely optical constant-force tweezing. The observed effect is attributed in a geometric optics model to a non-zero lateral component of the scattering force.
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