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Updated: Aug 29, 2026

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Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
Published on: August 7, 2018
Structural investigation of proapoptotic peptide by CD and NMR spectroscopy
Emy Pulsinelli1, Francesca Vasile, Laura Vergani
1Department of Biophysical Sciences and Technologies M.&O., University of Genoa, c.so Europa 30, Genoa, Italy.
Protein and Peptide Letters
|December 20, 2003
Abstract:
We have performed a systematic investigation of the structural features of the peptides Int (a sequence able to cross cell membranes) and Int-H1(S6A,F8A) (which shows interesting antitumoral properties). After screening in aqueous solution at different ionic strength and pH values, we analyzed the structures of the peptides in different water/trifluoroethanol mixtures by Circular Dichroism and Nuclear Magnetic Resonance techniques.

