Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Scotopic versus photopic pattern onset-offset electroretinograms.

S Pallas1, W Schmidt, E Dodt

  • 1Max-Planck-Institute for Physiological and Clinical Research, W. G. Kerckhoff-Institute, Bad Nauheim, Germany.

Documenta Ophthalmologica. Advances in Ophthalmology
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Directed evolution and Phenomics screening of new biocatalysts.

Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen)·2005
Same author

[Effect of cataracts on contrast pattern reversal stimuli exemplified by the pattern electroretinogram].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·1996
Same author

Simultaneously recorded retinal and cerebral potentials to windmill stimulation.

Documenta ophthalmologica. Advances in ophthalmology·1995
Same author

[Sensory and electrical responses in stimulation of the macula with short-wave (407-527 nm) linear polarized light (Haidinger polarization brushes)].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·1994
Same author

[Amblyopic eyes produce an abnormal electroretinogram in pattern presentation with the on-off technique].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·1994
Same author

[Results of treatment in vulvar cancer from 1970 to 1990].

Geburtshilfe und Frauenheilkunde·1992
Same journal

Effects of short-term moderate versus high intraocular pressure elevation on flicker-induced changes in full-field electroretinogram.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

The relationship between foveal anatomy and retinal function in oculocutaneous albinism.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Early onset primary angle closure and foveal retinoschisis associated with a pseudo-homozygous CRB1 pathogenic variant.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Bilateral perifoveal macular ischemia in non-proliferative Duchenne muscular dystrophy-associated retinopathy: a case report.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Association between dynamic pupil parameters and corneal sub-basal nerve plexus morphology.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Structure-function relationship between handheld photopic negative response and macular GCIPL thickness in chronic optic neuropathy.

Documenta ophthalmologica. Advances in ophthalmology·2026
See all related articles

Rods and cones contribute differently to the human pattern electroretinogram (PERG) based on light conditions and checkerboard size. The PERG response to reversing checkerboards is a mix of pattern and luminance information.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Visual Psychophysics

Background:

  • The human pattern electroretinogram (PERG) is a key diagnostic tool for visual pathway function.
  • Understanding the specific contributions of rods and cones to the PERG is crucial for interpreting results under various lighting conditions.

Purpose of the Study:

  • To investigate the distinct roles of rod and cone photoreceptors in generating the human PERG.
  • To analyze how spatial frequency, wavelength, and check size influence PERG responses under scotopic and photopic conditions.

Main Methods:

  • Recorded human PERG using onset/offset checkerboards of varying spatial frequencies and wavelengths (486-601 nm) under strictly scotopic and photopic conditions.
  • Examined PERG amplitude and polarity changes in response to different check sizes (from 3°30' to larger sizes).

Related Experiment Videos

Main Results:

  • Scotopic conditions showed a negative onset and positive offset potential, while photopic conditions exhibited a positive onset and mixed offset potential.
  • Photoreceptor sensitivity differences (486-601 nm) under scotopic/photopic conditions correlated with rod and cone luminosity functions, respectively.
  • Onset response amplitude varied with check size, indicating antagonistic center-surround organization, while offset response increased monotonically, suggesting a luminance component.

Conclusions:

  • The PERG waveform is influenced by both pattern-specific (contrast) and luminance-specific signals.
  • Rod and cone contributions to the PERG differ significantly under scotopic and photopic conditions.
  • The findings highlight the complex nature of the PERG and its dependence on stimulus parameters and retinal adaptation states.