Mutation screening of Mre11 complex genes: indication of RAD50 involvement in breast and ovarian cancer
Journal of Medical Genetics
|December 20, 2003
Abstract
No abstract available in PubMed .
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Mismatch Repair
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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.The Mutator Protein Family Plays a Key Role in DNA Mismatch RepairThe human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
