[Factors related to severe acute asthma in childhood - epidemiologic and clinical aspects]

J C Santana1, S S Barreto, P R Carvalho

  • 1Médico Pediatra Intensivista do Hosp. São Lucas-PUCRS, UFRGS.

Jornal De Pediatria
|December 20, 2003
PubMed

Insights

Severe acute asthma in children admitted to the pediatric intensive care unit (PICU) is linked to young age, family history of asthma or smoking, and prior hospitalizations. Effective medical care and early intervention are crucial for better outcomes.

Area of Science:

  • Pediatric Pulmonology
  • Epidemiology
  • Critical Care Medicine

Context:

  • Severe acute asthma necessitates pediatric intensive care unit (PICU) admission.
  • Understanding risk factors for severe asthma in children is crucial for effective management.
  • This study investigates epidemiologic and clinical factors associated with severe asthma in PICU admissions.

Purpose:

  • To identify epidemiologic and clinical factors associated with severe acute asthma in children requiring PICU admission.
  • To analyze precipitating factors, family history, and clinical course of severe asthma in pediatric patients.
  • To determine factors influencing hospitalization duration and complications like pneumonitis.

Summary:

  • Respiratory viral infections were the primary trigger for severe asthma attacks in 74% of cases.
  • A family history of asthma, atopy, or smoking was present in 97% of children.
  • Younger age (under 1 year), previous PICU admission, family history of smoking, and pneumonitis were associated with longer PICU stays.
  • Pneumonitis was a common complication, particularly in infants under one year receiving public healthcare.

Impact:

  • Identifies key risk factors for severe pediatric asthma, including age, family history, and prior hospitalizations.
  • Highlights the significant role of viral infections and pneumonitis in severe asthma exacerbations.
  • Suggests that early and aggressive management, alongside effective medical care, can improve clinical outcomes for children with severe acute asthma.
  • Emphasizes the low mortality rate for children with acute asthma requiring PICU admission.
Abstract

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.