Related Experiment Video

Updated: Aug 29, 2026

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
08:45

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation

Published on: June 27, 2025

[Hepatic veno-occlusive disease: report of a case]

E M Magnabosco1, M L Rivera, I R Prolla

  • 1Sextanista do Curso de Medicina da Universidade Federal de Santa Maria.

Jornal De Pediatria
|March 1, 1997
PubMed

Insights

Certain herbal teas, like "maria-mole" (Senecio brasiliensis), can cause Hepatic Veno-Occlusive Disease in children due to toxic pyrrolizidine alkaloids. Awareness and avoidance are crucial for preventing this serious liver condition.

Area of Science:

  • Pediatrics
  • Toxicology
  • Hepatology

Context:

  • Herbal teas are often perceived as harmless remedies.
  • Pyrrolizidine alkaloids (PAs) found in some plants are known hepatotoxins.
  • Hepatic Veno-Occlusive Disease (HVOD) is a serious vascular complication of the liver.

Purpose:

  • To alert pediatricians to the potential dangers of certain herbal teas.
  • To highlight a case of HVOD linked to herbal tea consumption.
  • To emphasize the need for increased awareness regarding toxic herbal products.

Summary:

  • A case report details a child who developed Hepatic Veno-Occlusive Disease (HVOD) and portal hypertension.
  • The condition was attributed to chronic consumption of the herbal tea "maria-mole" (Senecio brasiliensis), containing hepatotoxic pyrrolizidine alkaloids.
  • The patient fully recovered after treatment, underscoring the importance of identifying the causative agent.

Impact:

  • Increased physician and public awareness of the risks associated with "innocuous" herbal teas.
  • Potential reduction in pediatric cases of pyrrolizidine alkaloid-induced liver injury.
  • Highlights the critical role of toxicology in evaluating commonly consumed substances.
Abstract

More Related Videos

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices02:14

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Published on: August 1, 2025

Related Concept Videos

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Portal Hypertension01:22

Portal Hypertension

Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
Hepatic Portal System01:21

Hepatic Portal System

The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is responsible...
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...