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[Peptic disease: comparative study between children and adolescents]
M S Toporovski1, C B Neufeld, A M Chiara
1Santa Casa de São Paulo, São Paulo, SP, Brazil.
Jornal De Pediatria
|December 20, 2003
Summary
This study compared clinical and endoscopic findings in pediatric (CR) and adolescent (AD) peptic disease, revealing similar pain characteristics but distinct gastritis types and higher H. pylori rates in adolescents. Epigastric pain is a key symptom across both age groups.
Area of Science:
- Gastroenterology
- Pediatric Medicine
- Clinical Research
Background:
- Peptic disease presents unique challenges in pediatric and adolescent populations.
- Understanding age-specific clinical and endoscopic manifestations is crucial for accurate diagnosis and management.
Purpose of the Study:
- To conduct a comparative analysis of clinical and endoscopic data in peptic disease between children (CR) and adolescents (AD).
- To identify age-related differences in symptoms, endoscopic findings, and Helicobacter pylori colonization.
Main Methods:
- A study involving 30 children and 76 adolescents diagnosed with peptic disease via endoscopic and histologic examination.
- Comparison of clinical data, including abdominal pain characteristics, and endoscopic findings between the two groups.
- Statistical analysis using the Fisher Test to determine significant differences (p<0.05).
Main Results:
- Epigastric pain was significantly more prevalent in adolescents (87%) compared to children (63%).
- While endoscopic findings were normal in 30% of children, only 14% of adolescents had normal findings (p=0.052).
- Diffuse gastritis was more common in adolescents (72%) than children (37%) (p=0.01), with children showing predominantly antral nodular gastritis.
Conclusions:
- Epigastric pain is a primary symptom in both pediatric and adolescent peptic disease.
- Normal endoscopic findings are more frequent in children, highlighting potential diagnostic challenges.
- Helicobacter pylori colonization rates were higher in adolescents (52%) than in children (36%), and duodenal ulcers were more common than gastric ulcers in both groups.