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Updated: Aug 29, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Primary orbital plasmacytoma: A case report
Seema Sen1, Seema Kashyap, Subhash Betharia
1Department of Ocular Pathology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. ssenop@rediffmail.com
Abstract:
A 50-year-old man presented with a fungating growth in the left eye of 3 months duration. Biopsy of the mass followed by light microscopy was suggestive of plasmacytoma and the diagnosis was confirmed by immunohistochemical stains, which demonstrated monoclonality to kappa light chains. Systemic investigations ruled out a multiple myeloma. The patient received radiotherapy; however, due to a residual mass, the left orbit had to be exenterated. Solitary plasmacytomas may not always be completely radiosensitive and radical surgery may be required in such cases. Immunohistochemical stains for kappa and lambda light chains can prove useful in confirming the diagnosis of suspected plasmacytomas.