[Influence of sperm morphology on results of intrauterine insemination]
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Updated: Aug 29, 2026

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
Published on: November 29, 2018
Eric Saucedo de la Llata1, María Rosa Moraga Sánchez, Víctor Batiza Resendiz
1Instituto para el Estudio de la Concepción Humana (IECH), Monterrey, N.L.-Centro de Ginecología y Obstetricia de Monterrey, S.A. (CGOMSA).
Objective:
To determine the influence of sperm morphology, according to WHO criteria, on pregnancy rates of couples who were submitted to intra-uterine insemination (IUI).
Material And Methods:
Retrospective study that included 787 IUI cycles performed in the Instituto para el Estudio de la Concepción Humana in Monterrey, Mexico, from January to December 2002. Main diagnosis were anovulation, male factor, endometriosis, and cervical factor. All patients were allocated into a controlled ovarian hyperstimulation protocol with either clomiphene citrate, menotropins and/or recombinant FSH.
Results:
A total of 115 pregnancies were achieved (pregnancy rate per cycle of 14.61%). When seminal parameters were analyzed as independent factors it was found that a motility less than 10%, total motile count after sperm preparation less than 1 million/ml and sperm motility less than 20% had a pregnancy rate of zero.
Conclusions:
Patients with normal sperm forms less than 20% according to WHO criteria have no benefit with the IUI and these patients should be canalized to ART.
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