Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Simulate heart rate variability in different physiological conditions.

D C Lin1

  • 1Department of Mechanical, Aerospace & Industrial Engineering, Ryerson University, Toronto, Ontario, Canada. derlin@ryerson.ca

Computers in Cardiology
|December 23, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Application of internal mammary perforator as recipient vessels in immediate breast reconstruction using deep inferior epigastric perforator flaps in early breast cancer].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2025
Same author

Evaluation and management of patients with symptoms after anti-reflux surgery.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2013
Same author

Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis.

Allergy·2012
Same author

Integrated central-autonomic multifractal complexity in the heart rate variability of healthy humans.

Frontiers in physiology·2012
Same author

Common multifractality in the heart rate variability and brain activity of healthy humans.

Chaos (Woodbury, N.Y.)·2010
Same author

Involvement of the lipid and protein components of (Na(+) + K(+))-adenosine triphosphatase in the inhibitory action of alcohol.

Biochemical pharmacology·2010
Same journal

An Anisotropic Fluid-Solid Model of the Mouse Heart.

Computers in cardiology·2019
Same journal

Electrographic Response of the Heart to Myocardial Ischemia.

Computers in cardiology·2016
Same journal

Similarity-Based Searching in Multi-Parameter Time Series Databases.

Computers in cardiology·2010
Same journal

Predicting Acute Hypotensive Episodes: The 10th Annual PhysioNet/Computers in Cardiology Challenge.

Computers in cardiology·2010
Same journal

An Artificial Multi-Channel Model for Generating Abnormal Electrocardiographic Rhythms.

Computers in cardiology·2010
Same journal

An Open-Source Standard T-Wave Alternans Detector for Benchmarking.

Computers in cardiology·2010
See all related articles

Heart rate variability (HRV) multifractal analysis reveals how autonomic nervous system blockades affect heart rate regulation. Parasympathetic blockade shifts HRV mechanisms from multiplicative to additive, altering its complex dynamics.

Area of Science:

  • Physiology
  • Complex Systems Analysis
  • Autonomic Nervous System Research

Background:

  • Heart rate variability (HRV) exhibits multifractal properties, suggesting underlying cascade or multiplicative mechanisms.
  • Understanding these mechanisms is crucial for interpreting physiological regulation.
  • Autonomic nervous system (ANS) activity significantly influences HRV.

Purpose of the Study:

  • To investigate the impact of autonomic blockade on the multifractal properties of HRV.
  • To compare the effects of parasympathetic (PNS) and sympathetic (SNS) nervous system inhibition on HRV mechanisms.
  • To elucidate the specific changes in HRV dynamics under different ANS states.

Main Methods:

  • Numerical simulation of cascade perturbations in HRV.

Related Experiment Videos

  • Analysis of HRV multifractal characteristics.
  • Comparison of HRV data during PNS blockade versus SNS blockade.

    • Main Results:

    • A qualitative change in HRV multifractality was observed during PNS blockade.
    • This change indicates a shift in the underlying mechanism of HRV generation.
    • The observed shift was from a multiplicative mechanism to an additive mechanism.

    Conclusions:

    • Parasympathetic nervous system activity is critical for maintaining the multiplicative nature of HRV.
    • Autonomic blockade, particularly PNS blockade, fundamentally alters HRV dynamics.
    • The study provides insights into the complex interplay between the ANS and cardiac regulation through multifractal analysis.