Related Experiment Video
Updated: Aug 29, 2026
09:56
Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging
Published on: April 30, 2019
Mapping by waves. Patterned spontaneous activity regulates retinotopic map refinement
Stephen J Eglen1, Jay Demas, Rachel O L Wong
1Institute for Adaptive and Neural Computation, School of Informatics, University of Edinburgh, 5 Forrest Hill, Edinburgh, EH1 2QL, Scotland.
Neuron
|December 23, 2003
Abstract:
A role for spontaneous spiking activity in shaping neuronal circuits has frequently been debated. Analyses of retinotopy in mutant mice with reduced correlated firing among neighboring retinal cells by Grubb et al. and McLaughlin et al. in this issue of Neuron indicate the importance of patterned spontaneous activity for retinotopic map refinement in subcortical visual targets.
