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Updated: Aug 3, 2026

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Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
Published on: November 1, 2011
Vaccinia virus recombinant expressing gene of tick-borne encephalitis virus non-structural NS1 protein elicits
M V Khoretonenko1, M F Vorovitch, L G Zakharova
1Chumakov Institute of Poliomyelitis and Viral Encephalitides RAMS, Moscow, Russia.
Immunology Letters
|December 23, 2003
Abstract:
A vaccinia virus recombinant containing the non-structural tick-borne encephalitis virus (TBEV) NS1 gene was developed. The recombinant expressed native dimeric form of the NS1 protein in infected cells and protected mice against lethal infection with TBEV.

