Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postmenopausal bleeding due to chronic DIC.

Shrikant S Bollapragada1, Mamta Garg, Tom McFarlane

  • 1Obstetrics and Gynaecology Directorate, Stepping Hill Hospital, Stockport SK2 7JE, UK. bsshrikant@yahoo.com

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|December 23, 2003
PubMed
Summary

Postmenopausal bleeding can stem from chronic disseminated intravascular coagulation (DIC) due to aortic aneurysm. This rare cause was successfully managed with blood products and tranexamic acid.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical and immunological effects of adding cyclophosphamide to pomalidomide-dexamethasone in relapsed-refractory multiple myeloma: The randomized MUKseven trial.

British journal of haematology·2026
Same author

Prosthetic maintenance profiles and functional performance of single-implant mandibular overdentures in geriatric edentulism: A prospective clinical evaluation.

Bioinformation·2026
Same author

Early diagnosis of AL amyloidosis in haematology, cardiology, neurology, renal and general clinics: A British Society for Haematology Guideline.

British journal of haematology·2026
Same author

Real-world treatment patterns and outcomes in accelerated and blast-phase myeloproliferative neoplasms: Insights from a large multi-centre cohort analysis in the United Kingdom.

British journal of haematology·2026
Same author

Investigation and management of thrombocytosis without JAK2, CALR or MPL mutations: A British Society for Haematology Guideline.

British journal of haematology·2025
Same author

Management of relapsed multiple myeloma: A British Society of Haematology and UK Myeloma Society guideline.

British journal of haematology·2025

Area of Science:

  • Vascular Surgery
  • Hematology
  • Gynecology

Background:

  • Postmenopausal bleeding (PMB) necessitates thorough investigation to identify underlying causes.
  • Bleeding disorders are an infrequently cited cause of PMB, with limited documented cases.
  • Aortic aneurysms are rarely associated with systemic bleeding complications like disseminated intravascular coagulation (DIC).

Observation:

  • A patient presented with significant postmenopausal bleeding.
  • The bleeding was attributed to chronic disseminated intravascular coagulation (DIC).
  • The underlying cause of DIC was identified as a ruptured aortic aneurysm.

Findings:

  • This case highlights a rare etiology of postmenopausal bleeding: chronic DIC secondary to aortic aneurysm.

Related Experiment Videos

  • The patient's bleeding was effectively managed using a combination of blood product replacement and tranexamic acid.
  • Diagnostic workup included imaging to identify the aortic aneurysm and coagulation studies to confirm DIC.

    • Implications:

    • Clinicians should consider rare causes of postmenopausal bleeding, including DIC secondary to vascular pathology.
    • Prompt diagnosis and management of aortic aneurysms are crucial in patients with unexplained bleeding.
    • This case expands the understanding of the clinical manifestations of aortic aneurysms and DIC.