Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

MRI in migraineurs.

L Robbins1, H Friedman

  • 1University of Illinois, Chicago.

Headache
|November 1, 1992
PubMed
Summary
This summary is machine-generated.

Migraine patients showed a higher incidence of white matter lesions on MRI scans compared to controls. These lesions appeared in a younger demographic among migraineurs, suggesting potential ischemic or immune-related causes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Legionella pneumophila-induced visual learning impairment reversed by anti-interleukin-1 beta.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)·1995
Same author

delta 9-Tetrahydrocannabinol (THC) causes the variable expression of IL2 receptor subunits.

The Journal of pharmacology and experimental therapeutics·1995
Same author

Spatial learning impairment in mice infected with Legionella pneumophila or administered exogenous interleukin-1-beta.

Brain, behavior, and immunity·1995
Same author

MR imaging of the posterior cruciate ligament: normal, abnormal, and associated injury patterns.

Radiographics : a review publication of the Radiological Society of North America, Inc·1995
Same author

Detection of cerebrospinal fluid metastasis: CT myelography or MR?

AJNR. American journal of neuroradiology·1995
Same author

Gruesomeness, emotional attachment, and personal threat: dimensions of the anticipated stress of body recovery.

Journal of traumatic stress·1995
Same journal

Biochemical profiling and symptomatology of androgen deficiency in males with cluster headache: A prospective case-control study.

Headache·2026
Same journal

Thiamine deficiency in patients with chronic migraine: A case-control study.

Headache·2026
Same journal

Potential association of cluster headache with certain COVID-19 vaccines: An assessment from the pharmacovigilance databases.

Headache·2026
Same journal

Potential role of tirzepatide, a dual GLP-1 and GIP receptor agonist, for preventive treatment of migraine: A case series.

Headache·2026
Same journal

Adverse childhood experiences, migraine, and adverse pregnancy outcomes among teenage mothers.

Headache·2026
Same journal

Weight loss with atogepant in the long-term treatment of migraine: An interim analysis of a safety endpoint from a phase 3, multicenter, open-label, 156-week extension study.

Headache·2026
See all related articles

Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • Migraine is a common neurological disorder.
  • Intracranial pathology can manifest in various ways.
  • Magnetic Resonance Imaging (MRI) is a key diagnostic tool.

Purpose of the Study:

  • To investigate the incidence of intracranial pathology, specifically white matter lesions, in migraineurs compared to controls.
  • To analyze the age distribution of white matter lesions in migraineurs.

Main Methods:

  • Utilized MRI scans (axial and sagittal planes) with different pulse sequences (long TR/short TE, long TR/long TE, short TR/short TE).
  • Administered Gadolinium-Diethylenetriaminepentaacetic acid (Gd-DTPA) contrast enhancement in controls and some migraineurs.
  • Compared the prevalence of white matter lesions between 46 migraineurs and 69 age/sex-matched controls.

Related Experiment Videos

Main Results:

  • White matter lesions were observed in 13% of migraineurs (6/46) versus 4.3% of controls (3/69).
  • White matter lesions were identified in a younger age group among migraineurs compared to controls.
  • Findings align with existing MRI studies on migraine-related brain changes.

Conclusions:

  • Migraineurs exhibit a higher prevalence of white matter lesions than the general population.
  • Possible underlying mechanisms include cerebral ischemia or immune-mediated white matter demyelination.
  • Further research is warranted to elucidate the precise etiology and clinical significance of these lesions in migraine.