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Intravascular papillary endothelial hyperplasia of the extremities: MR imaging findings with pathologic correlation
Sang Hoon Lee1, Jin-Suck Suh, Byung Il Lim
1Department of Diagnostic Radiology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 132 Shinchondong, Seodaemoon-gu, 120-752 Seoul, Korea.
Abstract:
We report the MRI findings of three cases of intravascular papillary endothelial hyperplasia (IPEH) of the extremities with correlation of the pathologic findings. The IPEH is a non-neoplastic reactive lesion within the vessels and is commonly associated with thrombi. Signal intensity of the IPEH is complex due to the thrombi and the PEH itself. The thrombi are characterized by a slightly hyperintense signal on T1- and T2-weighted images compared with that of muscle when it comes at the medium stage of hemorrhage. Papillary endothelial hyperplastic tissue appears either as iso- or hyperintense to the muscle on T2- and T1-weighted images and shows variable enhancement on Gd-DTPA-enhanced images.
Insights
Intravascular papillary endothelial hyperplasia (IPEH) is a non-neoplastic vascular lesion. MRI reveals complex signal intensities in IPEH due to thrombi and hyperplastic tissue, aiding diagnosis.
Area of Science:
- Vascular Pathology
- Medical Imaging
- Radiology
Background:
- Intravascular papillary endothelial hyperplasia (IPEH) is a rare, non-neoplastic vascular lesion.
- IPEH is often associated with thrombi, complicating its imaging appearance.
- Understanding MRI characteristics is crucial for accurate diagnosis.
Observation:
- This study presents MRI findings in three cases of IPEH in the extremities.
- Correlations were made between MRI and pathological findings.
- IPEH lesions demonstrated complex signal intensities on MRI.
Findings:
- Thrombi within IPEH showed slightly hyperintense signals on T1- and T2-weighted images, indicative of subacute hemorrhage.
- Papillary endothelial hyperplastic tissue appeared isointense or hyperintense to muscle on T1- and T2-weighted images.
- Variable enhancement patterns were observed on Gd-DTPA-enhanced MRI sequences.
Implications:
- Accurate MRI interpretation can help differentiate IPEH from other vascular lesions.
- These findings contribute to the diagnostic imaging of IPEH.
- Improved understanding of IPEH MRI characteristics aids in clinical management.
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