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Related Experiment Videos

[Osteonecrosis and HELLP-Syndrome].

M Jäger1, A Wild, R Krauspe

  • 1Orthopädische Universitätsklinik, Heinrich-Heine Universität Düsseldorf, Düsseldorf, Germany. Jaeger@med.uni-duesseldorf.de

Zeitschrift Fur Geburtshilfe Und Neonatologie
|December 23, 2003
PubMed
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Early MRI screening is crucial for pregnant women experiencing bone pain to detect osteonecrosis. Prompt diagnosis and treatment of osteonecrosis, especially in HELLP syndrome patients, improve outcomes.

Area of Science:

  • Obstetrics and Gynecology
  • Orthopedic Surgery
  • Radiology

Background:

  • Pregnancy-associated osteonecrosis, particularly affecting the femoral head, occurs in women with Hemolysis- Elevated Liver enzymes- and Low Platelet count (HELLP) syndrome.
  • Risk factors for osteonecrosis include HELLP syndrome, steroid therapy, and advanced maternal age.
  • The subchondral femoral epiphysial head is the most common site due to anatomical and biomechanical factors.

Observation:

  • A case report details a 37-year-old HELLP patient with bilateral femoral head osteonecrosis.
  • The patient experienced a proximal femur fracture following bone marrow core decompression surgery.
  • Distinguishing early osteonecrosis from bone marrow edema syndrome and transient osteoporosis can be challenging.

Findings:

Related Experiment Videos

  • Early-stage osteonecrosis is potentially curable with timely intervention.
  • Steroid treatment for HELLP syndrome increases the risk of developing osteonecrosis.
  • Magnetic Resonance Imaging (MRI) is recommended for early detection of osteonecrosis in pregnant patients with bone pain.

    • Implications:

    • Early MRI screening in pregnant women with joint or bone pain is vital for detecting osteonecrosis.
    • Prompt diagnosis enables therapeutic interventions that can lead to successful outcomes.
    • Awareness of elevated osteonecrosis risk in HELLP patients undergoing steroid treatment is essential for patient management.