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Published on: January 28, 2020
C-reactive protein as a novel biomarker. Reactant can flag atherosclerosis and help predict cardiac events
Nader Elgharib1, David S Chi, Walid Younis
1Division of Allergy and Immunology, Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, PO Box 70622, Johnson City, TN 37614-1709, USA.
Insights
C-reactive protein (CRP) is an inflammation marker useful for monitoring cardiovascular diseases like coronary artery disease. It helps predict serious events in patients with acute coronary syndrome, myocardial infarction, or peripheral vascular disease.
Area of Science:
- Cardiology
- Inflammation markers
Background:
- C-reactive protein (CRP) is a nonspecific marker of inflammation.
- Its role in cardiovascular disease requires further elucidation.
Purpose of the Study:
- To review the role of CRP in the diagnosis, monitoring, and treatment of cardiovascular diseases.
- To highlight CRP's predictive value in specific cardiovascular conditions.
Main Methods:
- Literature review of studies on CRP in cardiovascular disease.
- Analysis of CRP's utility in acute coronary syndrome, myocardial infarction, and peripheral vascular disease.
Main Results:
- CRP can predict serious events in patients with coronary artery disease (CAD).
- It is useful for monitoring severity and progression in conditions like acute coronary syndrome and myocardial infarction (MI).
Conclusions:
- CRP serves as a valuable prognostic marker in various cardiovascular diseases.
- Understanding CRP's role aids in managing ischemic and inflammatory cardiovascular conditions.
Abstract:
C-reactive protein (CRP) is a relatively nonspecific marker of inflammation. However, it can be used to monitor the severity and progression of some well-defined cardiovascular diseases. For example, it can predict serious events in patients with coronary artery disease (CAD) who are hospitalized with acute coronary syndrome, myocardial infarction (MI), or advanced peripheral vascular disease. In this article, the authors review the role of CRP in the diagnosis, monitoring, and treatment of various forms of ischemic and inflammatory cardiovascular disease.
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