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[Treatment of chronic bacterial prostatitis by perfusion with double-balloon and triple-channel catheter: a control
Wei-Dong Huang1, Wen-Jie Huang, Pei Liu
1Xinjiang Jiayin Andrology Hospital, Urumuqi, Xinjiang 830011, China.
Insights
The double-balloon and triple-channel catheter (DBTC) shows superior efficacy in treating chronic bacterial prostatitis (CBP) compared to intravenous antibiotics. This novel transurethral approach offers a safe and effective alternative for CBP management.
Area of Science:
- Urology
- Infectious Diseases
- Medical Devices
Context:
- Chronic bacterial prostatitis (CBP) presents a persistent clinical challenge.
- Current treatment modalities for CBP have limitations in efficacy and patient outcomes.
- Novel therapeutic strategies are needed to improve CBP management.
Purpose:
- To evaluate the clinical efficacy of the double-balloon and triple-channel catheter (DBTC) for treating chronic bacterial prostatitis (CBP).
- To compare the outcomes of DBTC-based therapy with traditional intravenous antibiotics and saline irrigation.
Summary:
- A study involving 103 CBP patients compared DBTC transurethral perfusion with antibiotics, intravenous antibiotics, and saline irrigation.
- DBTC therapy demonstrated significantly higher improvement rates in clinical symptoms (81.9%), lecithin corpuscles (68.9%), white blood cell (WBC) decline (75.4%), and bacteriological efficacy (91.8%) compared to intravenous treatment.
- While DBTC showed a higher clinical efficacy, a small incidence of mild urethral allergic reactions was noted.
Impact:
- Transurethral DBTC offers a more effective and potentially safer treatment option for chronic bacterial prostatitis.
- The DBTC method provides advantages in terms of safety, efficacy, ease of use, and repeatability.
- This study supports the adoption of DBTC as a valuable tool in the urologist's armamentarium for CBP.
Objective:
To investigate the efficacy of the double-balloon and triple-channel catheter (DBTC) in the treatment of chronic bacterial prostatitis (CBP).
Methods:
One hundred and three CBP patients were randomly assigned to three different groups and received three different therapies, respectively: 1. 61 cases by transurethral perfusion and drainage with antibiotics with DBTC catheter; 2. 29 cases by intravenous antibiotics, and 3. 13 cases by transurethral irrigation with 0.9% saline. The lecithin, white blood cells (WBC) in expressed prostatic secretion (EPS) and Meares-Stamey's test fractionary urine culture pre- and post-therapies were compared.
Results:
The improvement rates of clinical symptoms and lecithin corpuscles were 81.9% and 68.9%, respectively. And the decline rate of WBC and bacteriological efficacy rate were 75.4% and 91.8%, respectively. There was a significant statistical difference between the DBTC group and the intravenous group in the lecithin, WBC and bacterial culture (P < 0.05, < 0.01 and < 0.01, respectively), and so was there between the saline group and the intravenous group in the decline of WBC(chi 2 = 5.6, P < 0.05), but with no difference in lecithin and bacterial culture. Among 61 patients treated with DBTC, 3 developed mild allergic reaction in urethra.
Conclusions:
Transurethral DBTC has a better clinical efficacy than traditional intravenous treatment for CBP. DBTC perfusion combined with other hypurgia holds obvious advantages of being safe, effective, easy and repeatable in the treatment of CBP.
