Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vascularized bone transfer.

C S Han1, M B Wood, A T Bishop

  • 1Department of Orthopedics, Mayo Clinic, Rochester, Minnesota 55905.

The Journal of Bone and Joint Surgery. American Volume
|December 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of prior COVID-19 infection with gestational diabetes mellitus.

Diabetes research and clinical practice·2026
Same author

Microcomputed analysis of nerve angioarchitecture after combined stem cell delivery and surgical angiogenesis to nerve allograft.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2021
Same author

Serine Metabolism Controls Dental Pulp Stem Cell Aging by Regulating the DNA Methylation of p16.

Journal of dental research·2020
Same author

Accuracy of automated three-dimensional ultrasound imaging technique for fetal head biometry.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2020
Same author

ALK-positive anaplastic large-cell lymphoma with primary bone involvement: A rare case and review of the literature.

The Malaysian journal of pathology·2018
Same author

Variants of Monteggia Type Injury: Case Reports.

Malaysian orthopaedic journal·2017

Vascularized bone grafts from the iliac crest or fibula successfully reconstructed skeletal defects in 160 patients. Overall union rates reached 81%, demonstrating this technique

Area of Science:

  • Orthopedic Surgery
  • Reconstructive Surgery
  • Bone Grafting

Background:

  • Large skeletal defects pose significant reconstructive challenges.
  • Vascularized bone grafts offer a potential solution for complex bone loss.
  • Previous studies have shown variable outcomes for bone reconstruction procedures.

Purpose of the Study:

  • To evaluate the efficacy of vascularized bone grafts for skeletal defect reconstruction.
  • To assess union rates and functional recovery following iliac crest or fibula grafts.
  • To identify factors influencing the success of vascularized bone transfer.

Main Methods:

  • Retrospective analysis of 160 consecutive patients undergoing vascularized bone grafting (iliac crest or fibula).
  • Indications included tumor resection defects, trauma, osteomyelitis, and congenital anomalies.

Related Experiment Videos

  • Follow-up averaged 42 months, assessing union and functional outcomes.

    • Main Results:

    • Primary union rate was 61%, with an overall union rate of 81% after secondary procedures.
    • For patients with primary union and no further treatment, union averaged 6 months and full activity 16 months.
    • Higher success rates were observed in reconstructions for tumor resection, congenital anomalies, and non-infected non-unions.

    Conclusions:

    • Vascularized bone transfer is a valuable option for reconstructing large skeletal defects in selected patients.
    • Outcomes are more favorable for tumor resection, congenital anomalies, and non-infected non-unions compared to osteomyelitis.
    • This technique provides a reliable method for achieving bone union and functional restoration.