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Predictive Immune Modeling of Solid Tumors
Published on: February 25, 2020
Exploring the immunogenome with bioinformatics
Bernard de Bono1, John Trowsdale
1MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. bdb@mrc-lmb.cam.ac.uk
Seminars in Immunology
|December 24, 2003
Abstract:
A better description of the immune system can be afforded if the latest developments in bioinformatics are applied to integrate sequence with structure and function. Clear guidelines for the upgrade of the bioinformatic capability of the immunogenetics laboratory are discussed in the light of more powerful methods to detect homology, combined approaches to predict the three dimensional properties of a protein and a robust strategy to represent the biological role of a gene.
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