Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Widespread livedoid vasculopathy.

Angelo V Marzano1, Miriam Vanotti, Elvio Alessi

  • 1Institute of Dermatological Sciences, University of Milan, Italy.

Acta Dermato-Venereologica
|December 24, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Type I and II Interferon Signalling Characterizes the Transcriptional Landscape of Sweet Syndrome.

Experimental dermatology·2026
Same author

Real-World Long-Term Effectiveness and Safety of Secukinumab in Psoriasis: Up to 7 Years of Evidence from the Italian Landscape Psoriasis (IL PSO) Multicenter Retrospective Study.

Dermatology and therapy·2026
Same author

Role of the IL-15 pathway in vitiligo: Mechanistic insights and therapeutic implications.

The Journal of investigative dermatology·2026
Same author

Trichophyton mentagrophytes Genotype VII: Sexually Transmitted Infection Beyond MSM.

The Australasian journal of dermatology·2026
Same author

Criteria for Hidradenitis Suppurativa Competence Centers.

Dermatology and therapy·2026
Same author

Exploratory Volatilome Profiling of Inflammation in Skin Fibroblasts: A Proof-of-Concept Study.

International journal of molecular sciences·2026

This case study highlights livedoid vasculopathy, a rare skin condition. Effective treatment involved methylprednisolone and pentoxifylline, showing good response despite normal coagulation parameters.

Area of Science:

  • Dermatology
  • Rheumatology
  • Internal Medicine

Background:

  • Livedoid vasculopathy is a rare dermatosis.
  • It can be associated with systemic autoimmune disorders or present as an idiopathic form.
  • The idiopathic form is considered a non-inflammatory thrombotic disease, potentially linked to coagulation abnormalities.

Observation:

  • A 37-year-old woman presented with a 13-year history of livedo reticularis and recurrent painful ulcerative skin lesions.
  • She experienced a relapse involving widespread skin lesions, malar erythema, edema, alopecia, and fever.
  • Routine labs, immunological tests, and coagulation parameters were normal.

Findings:

  • Histological examination confirmed livedoid vasculopathy.
  • The patient achieved a good clinical response with intravenous methylprednisolone and pentoxifylline.

Related Experiment Videos

  • Despite extensive cutaneous manifestations, no serious systemic complications or abnormal seroimmunologic/coagulative profiles were observed.

    • Implications:

    • This case underscores that livedoid vasculopathy can present with significant cutaneous disease without systemic involvement or detectable coagulation issues.
    • It suggests the potential efficacy of methylprednisolone and pentoxifylline in managing livedoid vasculopathy.
    • Further research may clarify the pathogenesis of idiopathic livedoid vasculopathy and its management.