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Pyoderma gangrenosum, polycythemia rubra vera, and the development of leukemia
K K Ho1, B W Otridge, E Vandenberg
1Regional Centre of Dermatology, Mater Misericordiae Hospital, Dublin, Ireland.
Journal of the American Academy of Dermatology
|November 1, 1992
Abstract:
A patient with long-standing, well-controlled polycythemia rubra vera developed recurrent episodes of bullous pyoderma gangrenosum followed by the transformation of his hematologic disease into a rapidly progressive acute myeloid leukemia. This case, together with previously described patients, indicates that the appearance of bullous pyoderma gangrenosum in a patient with polycythemia rubra vera is often of ominous prognostic significance.