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Noninflammatory bullae associated with epsilon-aminocaproic acid infusion
C P Brooke1, E M Spiers, E F Omura
1Department of Dermatology, University of Alabama, Birmingham.
Journal of the American Academy of Dermatology
|November 1, 1992
Abstract:
Three patients who had cardiac surgery developed a transient, noninflammatory subepidermal bullous eruption on the legs after epsilon-aminocaproic acid infusion. Fibrin thrombi were demonstrated in papillary dermal vessels. The use of epsilon-aminocaproic acid as an antifibrinolytic agent may predispose patients to cutaneous vascular thromboses.