Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Methanol poisoning.

J A Kruse1

  • 1Division of Critical Care Medicine, Wayne State University School of Medicine, Detroit Receiving Hospital, Michigan.

Intensive Care Medicine
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Methanol poisoning, though rare, is dangerous, causing severe metabolic issues and potentially death. Prompt diagnosis and treatment with fomepizole or ethanol, alongside supportive care, are crucial for survival and preventing long-term harm.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

["Utilitarian system" : Heine's legacy poem "legs, to each man two were given" with his lyrical comments on the field of urology].

Der Urologe. Ausg. A·2015
Same author

Dopamine-1 receptor stimulation attenuates the vasoconstrictive response to gut ischemia.

Journal of applied physiology (Bethesda, Md. : 1985)·2001
Same author

Metformin-associated lactic acidosis.

The Journal of emergency medicine·2001
Same author

E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators.

JAMA·2001
Same author

Gut mucosal-arterial Pco2 gradient as an indicator of splanchnic perfusion during systemic hypo- and hypercapnia.

Critical care medicine·2000
Same author

Methemoglobinemia induced by topical anesthesia: a case report and review.

The American journal of the medical sciences·2000
Same journal

Rethinking phenotyping in acute respiratory failure: systemic inflammation can be infectious or noninfectious.

Intensive care medicine·2026
Same journal

Letters to the editor or correspondence written opaquely by AI/LLMs: a rising plague in science, but on whose shoulders does the onus of proof lie?

Intensive care medicine·2026
Same journal

Vitamin C in acute critical illness: don't confuse pharmacotherapy and nutrition!

Intensive care medicine·2026
Same journal

Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome.

Intensive care medicine·2026
Same journal

60 years of ARDS and the evolution of extracorporeal lung support - from ECMO to ECCO<sub>2</sub>R.

Intensive care medicine·2026
Same journal

Publisher Correction: Current knowledge and challenges of sepsis-associated encephalopathy.

Intensive care medicine·2026
See all related articles

Area of Science:

  • Toxicology
  • Emergency Medicine
  • Internal Medicine

Background:

  • Methanol ingestion is a rare but life-threatening poisoning.
  • It leads to severe metabolic disturbances, blindness, neurologic dysfunction, and death.
  • Methanol is metabolized to toxic formic acid in vivo.

Purpose of the Study:

  • To highlight the importance of prompt recognition and diagnosis of methanol poisoning.
  • To outline current therapeutic strategies for methanol intoxication.
  • To emphasize the potential benefits of specific antidotal and supportive treatments.

Main Methods:

  • Diagnosis relies on clinical suspicion and laboratory findings.
  • Key laboratory findings include metabolic acidosis with increased anion and osmol gaps.

Related Experiment Videos

  • Therapeutic measures involve supportive care and specific antidotes.

    • Main Results:

    • Specific treatments include sodium bicarbonate for acidosis and ethanol or fomepizole to inhibit methanol metabolism.
    • Hemodialysis aids in eliminating methanol and formic acid and corrects acidosis.
    • Folic acid may enhance formic acid metabolism.

    Conclusions:

    • Prompt diagnosis and institution of specific therapy can significantly reduce morbidity and mortality.
    • Early intervention is critical for favorable outcomes in methanol poisoning.
    • A high index of suspicion is necessary for timely and effective management.