Synchronous sebaceous lymphadenoma with squamous cell carcinoma - case report

Area of Science:

• Oncology
• Pathology
• Otolaryngology

Background:

• Sebaceous lymphadenoma is a rare benign salivary gland tumor with unclear origins.
• Synchronous occurrence of multiple neoplasms (benign or malignant) is uncommon.
• Parotid gland tumors require accurate diagnosis and management.

Purpose of the Study:

• To report a unique case of synchronous sebaceous lymphadenoma and squamous cell carcinoma in the parotid gland.
• To highlight the diagnostic challenges and implications of rare tumor combinations.
• To contribute to the literature on rare salivary gland neoplasms.

Main Methods:

• A case report of a 68-year-old female patient with parotid swelling.
• Fine needle aspiration cytology (FNAC) for initial diagnosis.
• Surgical excision (total conservative parotidectomy) and histopathological examination for definitive diagnosis.

Main Results:

• Initial FNAC suggested pleomorphic adenoma.
• Histopathology confirmed the presence of both sebaceous lymphadenoma and squamous cell carcinoma.
• This represents the first reported case of synchronous occurrence of these two entities in the parotid gland.

Conclusions:

• Sebaceous lymphadenoma and squamous cell carcinoma are individually rare salivary gland neoplasms.
• The synchronous occurrence of these distinct benign and malignant tumors in the parotid gland is exceptionally rare and previously unreported.
• This case underscores the importance of thorough histopathological evaluation for accurate diagnosis of parotid gland lesions.