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Updated: Aug 29, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Neoadjuvant chemotherapy for bladder cancer
Randall Millikan1, Arlene Siefker-Radtke, H Barton Grossman
1Department of Genitourinary Medical Oncology, Genitourinary Center, University of Texas, M.D. Anderson Cancer Center, Houston, TX 77033, USA. rmillika@mdanderson.org
Abstract:
While it is now clear that chemotherapy can contribute to improved outcome for some patients with muscle invasive bladder cancer, selection criteria for this very heterogeneous disease are lacking. The authors make an appeal for a biologically (in contrast to anatomically) based staging system, and urge that perioperative chemotherapy be given with standard combinations with curative intent.
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