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Disseminated lupus vulgaris
Paolo Gisondi1, Marie Perez, Emanuela Gubinelli
1Istituto Dermopatico dell'Immacolata, IRCCS, Via Monti Di Creta 104, 00167 Rome, Italy.
European Journal of Dermatology : EJD
|December 25, 2003
Summary
Lupus vulgaris, a rare skin tuberculosis form, can present with widespread lesions, not just facial ones. Early diagnosis via histology and PCR, followed by chemotherapy, ensures effective treatment and prevents internal organ involvement.
Area of Science:
- Dermatology
- Infectious Diseases
- Microbiology
Background:
- Lupus vulgaris is the most frequent type of cutaneous tuberculosis.
- It typically manifests as a single facial lesion.
Observation:
- Two cases of lupus vulgaris with multiple, widespread lesions are presented.
- Lesions spread on one patient after topical corticosteroid use.
- The second patient had extensive plaques on the scalp and inguinal regions.
Findings:
- Diagnosis was confirmed by histology and polymerase chain reaction (PCR) despite negative Ziehl-Neelsen staining.
- Neither patient exhibited internal organ (visceral) involvement.
- Antituberculosis polychemotherapy proved highly effective.
Implications:
- This highlights the varied presentation of cutaneous tuberculosis.
- It underscores the importance of advanced diagnostic methods beyond traditional staining.
- Prompt chemotherapy is crucial for managing extensive lupus vulgaris.