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"Isolated" postinfectious myoclonus
K Bhatia1, P D Thompson, C D Marsden
1Institute of Neurology, London, UK.
Journal of Neurology, Neurosurgery, and Psychiatry
|November 1, 1992
Summary
Two cases of isolated post-infectious myoclonus (IPIM) following influenza and chickenpox are presented. These cases highlight IPIM as a distinct post-infectious neurological syndrome.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Post-infectious syndromes can manifest with diverse neurological symptoms.
- Distinguishing specific neurological sequelae after infections is crucial for accurate diagnosis and management.
Observation:
- Two pediatric cases presented with myoclonus as the sole neurological symptom after viral infections (influenza-like illness and chickenpox).
- Neither case exhibited signs of encephalitis or opsoclonus-myoclonus syndrome.
- Investigations revealed no localizing neurological signs or abnormalities.
Findings:
- Generalized myoclonus occurred in one case post-influenza.
- Segmental myoclonus of the upper limb was observed in the other case post-chickenpox.
- Both patients achieved complete recovery within six months.
Implications:
- The term "isolated post-infectious myoclonus" (IPIM) is proposed for these distinct cases.
- Recognizing IPIM aids in differentiating it from other post-infectious neurological disorders.
- This condition appears to have a favorable prognosis with complete resolution.
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