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"Isolated" postinfectious myoclonus

K Bhatia1, P D Thompson, C D Marsden

  • 1Institute of Neurology, London, UK.

Journal of Neurology, Neurosurgery, and Psychiatry
|November 1, 1992
PubMed

Insights

Two cases of isolated post-infectious myoclonus (IPIM) following influenza and chickenpox are presented. These cases highlight IPIM as a distinct post-infectious neurological syndrome.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Pediatrics

Background:

  • Post-infectious syndromes can manifest with diverse neurological symptoms.
  • Distinguishing specific neurological sequelae after infections is crucial for accurate diagnosis and management.

Observation:

  • Two pediatric cases presented with myoclonus as the sole neurological symptom after viral infections (influenza-like illness and chickenpox).
  • Neither case exhibited signs of encephalitis or opsoclonus-myoclonus syndrome.
  • Investigations revealed no localizing neurological signs or abnormalities.

Findings:

  • Generalized myoclonus occurred in one case post-influenza.
  • Segmental myoclonus of the upper limb was observed in the other case post-chickenpox.
  • Both patients achieved complete recovery within six months.

Implications:

  • The term "isolated post-infectious myoclonus" (IPIM) is proposed for these distinct cases.
  • Recognizing IPIM aids in differentiating it from other post-infectious neurological disorders.
  • This condition appears to have a favorable prognosis with complete resolution.

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