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Updated: Jul 27, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Treatment of the obstructive sleep-apnea syndrome in adults]
A Hoekema1, P J Wijkstra, C T Buiter
1Afd. Mondziekten, Kaakchirurgie en Bijzondere Tandheelkunde, Academisch Ziekenhuis, Postbus 30.001, 9700 RB Groningen. a.hoekema@kchir.azg.nl
Abstract:
When treating the obstructive sleep-apnoea syndrome (OSAS), conservative management and the correction of treatable stenoses in the upper airway should be considered first. If these measures are neither effective nor applicable, then continuous positive airway pressure (CPAP) is the preferred treatment. Surgical interventions should only be considered after failure of non-surgical treatment modalities. Pharmacological management of OSAS is usually only indicated as a form of supplementary treatment in specific patients. Oral-appliance therapy appears to be of value in the management of OSAS and, in specific groups of patients, seems likely to offer a good alternative to CPAP in the future.
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