Related Experiment Video
Updated: Aug 18, 2026

Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica
Published on: October 28, 2022
[Study on the prevention, control and elimination of pneumoconiosis in fluorite mine]
1Institute of Industrial and Environmental Hygiene, College of Medicine, Zhejiang University, Hangzhou 310031, China.
Objective:
To prevent pneumoconiosis by strengthening comprehensive dust-proof and controlling its pathogenesis, and to discuss feasibility of pneumoconiosis elimination in our country.
Methods:
Comprehensive dust-proof was used for reducing the concentration of dust. Epidemiological investigation of pneumoconiosis was employed for evaluating the efficiency of pneumoconiosis prevention. Prospective tracking investigation was used for identifying the feasibility of the pneumoconiosis elimination.
Results:
The outcomes of dynamic observation of 35 years from 1962 to 1996 and results of prospective thirty years tracking investigation showed that after comprehensive dustp-roof, the average dust concentration and time weighted mean dust concentration in workers' operating conditions decreased from 366.0 mg/m3 and 163.4 mg/m3 to 1.2 mg/m3 and 1.3 mg/m3 respectively, and the declined rates reached 99.7% and 92.1%, respectively. After controlling pneumoconiosis pathogensis, the incidence rate of pneumoconiosis, its prevalence rate and mortality rate decreased from 24.8%, 85.5% and 5.9% to zero respectively.
Conclusion:
The thirty years prospective tracking investigation validated that the incidence of pneumoconiosis was zero. So the goal to eliminate pneumoconiosis was achieved.
Related Concept Videos
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pneumothorax-II
Clinical Manifestations:
Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...

