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Antibacterial xanthones from the leaves of Garcinia nigrolineata
Vatcharin Rukachaisirikul1, Mayuree Kamkaew, Dusadee Sukavisit
1Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkhla, 90112, Thailand. rvatchar@ratree.psu.ac.th
Abstract:
Ten new 1,3,5-trioxygenated xanthones, nigrolineaxanthones J-S (1-10), one new quinone derivative, nigrolineaquinone A (11), and one new isoflavone-like compound, nigrolineaisoflavone A (12), were isolated from the leaves of Garcinia nigrolineata along with four known xanthones and friedelin. Among the xanthones, only nigrolineaxanthone N (5) showed significant antibacterial activity against methicillin-resistant Staphylococcus aureus.
